Acetazolamide

A combination of acetazolamide and eszopiclone taken for 3 days lessened obstructive sleep apnea severity in adults, according to results published in Annals of the American Thoracic Society.

A combination pharmacotherapy for obstructive sleep apnea led to greater reductions in disease severity compared with placebo, according to results from a proof-of-concept phase 2 trial.

Acetazolamide taken during stays in high-altitude areas decreases the chances for altitude-related adverse health effects among patients with COPD, according to a European Respiratory Society International Congress presentation.

IV acetazolamide or placebo for decongestion in patients with acute decompensated HF on loop diuretics.

In the ADVOR trial, the addition of IV acetazolamide to standard IV loop diuretics improved acute congestion at 3 days in nearly 50% more patients vs. placebo in the setting of acute decompensated HF and volume overload.

According to the April 2, 2019, FDA drug shortages list, there were 270 current drugs in shortage across 26 therapeutic fields. The ophthalmic drugs in shortage included drugs utilized for both diagnostic and therapeutic indications.