Acetaminophen
Prenatal acetaminophen may be linked to childhood ADHD diagnosis, more review needed
Maternal acetaminophen exposure identified via second-trimester blood samples may be associated with higher odds of a childhood ADHD diagnosis in offspring, but more research is needed, researchers reported in Nature Mental Health.
Acetaminophen increases risk for hypertension, GI bleeding in patients 65 years and older
Patients aged 65 years and older who use acetaminophen demonstrate greater risks for serious complications, including hypertension, chronic kidney disease and gastrointestinal bleeding, noted a study published in Arthritis Care & Research.
Acetaminophen lowers acute respiratory distress syndrome development in sepsis
SAN DIEGO — Fewer patients with sepsis receiving acetaminophen vs. placebo developed acute respiratory distress syndrome, according to research presented at the American Thoracic Society International Conference.
Changes in prescription medication use by pregnant women after 2010 in US
Opioid and teratogenic medication prescriptions decreased and prescriptions for medications for diabetes and mental health conditions increased among pregnant women after 2010 in the U.S., researchers reported.
New guidelines address management of acetaminophen poisoning
A panel of experts chosen by four leading United States and Canadian clinical toxicology societies have developed clinical recommendations for the management of acetaminophen poisoning in ED settings.
FDA limit on acetaminophen dosage linked to fewer hospitalizations, cases of liver failure
A 2011 FDA mandate, which limited acetaminophen dosage to 325 mg/tablet in prescription acetaminophen and opioid products, correlated with a decrease in yearly hospitalizations and cases of acute liver failure related to toxicity.
FDA’s acetaminophen-opioid mandate linked to reductions in acute liver failure
An FDA mandate limiting acetaminophen in medications combining acetaminophen and opioids was associated with a reduction in serious liver injuries, a recent study in JAMA found.
‘Appreciating neuroplasticity’ may be key to developing effective osteoarthritis therapies
SAN DIEGO — The key to developing effective therapies for the management of osteoarthritis may lie in appreciating neuroplasticity in patients with the disease, according to a speaker at the Congress of Clinical Rheumatology West.
Two-thirds of older adults with joint pain use OTC therapies to manage pain
Most older adults with joint pain feel they can manage said pain without physician assistance, while 66% report they treat their joint pain with over-the-counter drugs such as acetaminophen or ibuprofen, according to a poll.
Acetaminophen may confer high BP in patients with CV risks
In patients with CV risks, there was a correlation between acetaminophen use and elevated systolic BP, according to a meta-analysis in the European Journal of Preventive Cardiology.