Ace Inhibitor
Antihypertensives at bedtime confer improved BP control vs. morning medications
Patients with hypertension who took BP-lowering medications at bedtime had improved ambulatory BP control compared with those who took medications when they woke up, which led to a reduction in major CVD events, according to a study published in the European Heart Journal.
Thiazide superior to ACE inhibitors for hypertension, frequent drinking important risk factor in AF — top stories in cardiology
LEGEND-HTN: Thiazide, thiazide-like diuretics superior to ACE inhibitors
Drug classes used as monotherapy for hypertension were shown to be comparable, although thiazide or thiazide-like diuretics were superior to ACE inhibitors, according to results from the LEGEND-HTN study published in The Lancet.
Intervention improves adherence to Mediterranean diet, intermittent statin dosing shows promise — top stories in cardiology
Angiotensin receptor blockers may increase risk for suicide
Patients treated with angiotensin receptor blockers had an increased risk for suicide compared with those treated with ACE inhibitors, according to a study published in JAMA Network Open.
Bias against higher recommended drug doses for HF may be present
The uptitration of drugs used to treat patients with chronic systolic HF was more likely to be stopped as the dosage became further away from the recommendation dose, especially with higher recommended dosages compared with lower recommended dosages, according to a brief research report published in the Annals of Internal Medicine.
Complete revascularization superior to culprit lesion-only PCI for STEMI, multivessel CAD: COMPLETE
PARIS — Complete revascularization was superior to culprit lesion-only PCI for reducing risk for CV death or MI in patients with STEMI and multivessel CAD, according to results from the COMPLETE trial presented at the European Society of Cardiology Congress.
PARAGON-HF: Sacubitril/valsartan misses primary endpoint for HFpEF; may still provide insight into unmet need
PARIS — Sacubitril/valsartan did not reduce the rate of hospitalizations for CV-related death and HF in patients with HF with preserved ejection fraction, defined as at least 45%, according to a hot line trial presented at the European Society of Cardiology Congress.
Medicare could save 90% on hypertension medications by switching to generic drugs
Medicare could have saved nearly 90% of spending on angiotensin converting enzyme inhibitors and angiotensin-II-receptor blockers in 2016 and 2017 through generic substitute or therapeutic interchange, according to study results published in JAMA Internal Medicine.
Patient-specific pharmacotherapy plan may reduce HF hospitalizations
HF remains a complex clinical syndrome. It is estimated that nearly 6 million Americans have HF and more than 800,000 new cases of HF are diagnosed annually in the United States.