Spondyloarthropathies News

CHICAGO — Nearly 50% of patients with axial spondyloarthritis are affected by chronic widespread pain, with women reporting higher pain intensity and sensitivity than men, according to data presented at ACR/ARHP 2018 Annual Meeting.

CHICAGO — Ixekizumab was superior to placebo in reducing disease activity while improving function, as well as spinal and sacroiliac joint inflammation among patients with ankylosing spondylitis, according to phase 3 data from the COAST-V trial.

CHICAGO — Researchers developed three algorithms that successfully identified patients with axial spondyloarthritis.

CHICAGO — Research presented at the ACR/ARHP 2018 Annual Meeting showed that secukinumab, a treatment for ankylosing spondylitis, was effective against multiple features of the disease over 5 years.

CHICAGO — Analysis of bone marrow edema, including the anatomical location, may help differentiate axial spondyloarthritis from other conditions, according to data from the MASH study presented at the ACR/ARHP 2018 Annual Meeting.

The FDA has approved the third biosimilar to adalimumab, adalimumab-adaz, for all eligible indications of the biologic product, according to a company press release.

CHICAGO — Genetic risk score has a high discriminatory capacity, performs at least as well as MRI — while being far less expensive — and could be of clinical use in the early diagnosis of ankylosing spondylitis, according to data presented at the ACR/ARHP 2018 Annual Meeting.

Among white patients with ankylosing spondylitis, presence of the human leukocyte antigen B27 protein is linked to an earlier disease onset and higher family aggregation, according to findings published in Arthritis Research & Therapy.

More than 50% of adults aged 45 years or older with some form of arthritis are currently going untreated, despite a substantial proportion experiencing severe symptoms and poor physical function, according to data published in the Journal of Clinical Rheumatology.

Researchers successfully used machine learning to detect flares among patients with rheumatoid arthritis and axial spondyloarthritis, and to determine a strong association between patient-reported flares and less physical activity, according to recent findings in Arthritis Care & Research.