Scleroderma News

A hypochromic red cells concentration of more than 2% is an independent predictor of mortality in patients with systemic sclerosis, according to data published in Arthritis Research & Therapy.

The use of proton pump inhibitors improves overall and progression-free survival in patients with systemic sclerosis-associated interstitial lung disease, according to data published in Rheumatology.

Rituximab was associated with significant improvements in both skin and lung parameters over long-term follow-up in a cohort of patients with systemic sclerosis, according to a study.

A fully automated analysis of nailfold images was able to distinguish patients with systemic sclerosis from those with normal capillaries at least as well as human experts, according to data published in Rheumatology.

Patients with systemic sclerosis who report more severe reflux symptoms demonstrate worse interstitial lung disease outcomes despite receiving standard therapy, according to data published in Arthritis Care & Research.

The FDA has granted Orphan Drug Designation to belimumab, a B-cell inhibiting monoclonal antibody, for the potential treatment of systemic sclerosis, according to a press release from GlaxoSmithKline.

Randomized controlled trials investigating systemic sclerosis do a poor job of documenting the race, ethnicity and socioeconomic status of participants, according to data published in Arthritis Care & Research.

It may be possible to use the signature of classical and non-classical circulating monocytes to stratify patients with systemic sclerosis and predict disease severity and outcomes, according to data published in Arthritis & Rheumatology.

PHILADELPHIA — Vision Transformer, an open-source computer algorithm, may detect changes in nailfold capillaroscopy images in patients with systemic sclerosis, according to data presented at ACR Convergence 2022.

PHILADELPHIA — A daily glucocorticoid dose higher than 2.5 mg may lead to irreversible bone mineral density loss regardless of intervention with osteoporosis medications, according to data presented at ACR Convergence 2022.