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Rheumatoid Arthritis News
VIDEO: ACR guidelines for managing patients with RA
In this video, Dana DiRenzo, MD, MHS, instructor of medicine at Johns Hopkins, discussed a session on the new ACR recommendations for managing patients with rheumatoid arthritis.
'Just 30 days of glucocorticoid use' in RA spikes cardiovascular risk by 15% over 6 months
Among patients with rheumatoid arthritis, 30 days of glucocorticoid use in 6 months is associated with 15% increased odds of major adverse cardiac events in the next 6 months, according to data presented at ACR Convergence 2021.
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Breakthrough COVID-19 infection risk highest in RA, gout, polydermatomyositis, vasculitis
Patients with rheumatoid arthritis, gout, polydermatomyositis, vasculitis and those with multiple rheumatic diseases were at greatest risk for breakthrough COVID-19 infection, despite full or partial vaccination vs. those without rheumatic disease.
Rate of major cardiovascular events in RA higher for tofacitinib vs. TNF inhibitors
Tofacitinib is associated with a numerically higher incidence of major adverse cardiac events, versus TNF inhibitors, in patients with rheumatoid arthritis at an increased cardiac risk, according to data presented at ACR Convergence 2021.
Job loss, 'dose of poverty' worsen disability, mortality outcomes in rheumatic diseases
Unemployment and poverty can be significant drivers of poor outcomes in conditions like rheumatoid arthritis and systemic lupus erythematosus, according to a keynote lecture at ACR Convergence 2021.
'Cycling' JAK inhibitors effective in difficult-to-treat rheumatoid arthritis
Patients with rheumatoid arthritis who fail their first JAK inhibitor can achieve success with either “cycling” to another JAK inhibitor or switching to a biologic disease-modifying antirheumatic drug, according to data presented at ACR Convergence 2021.
Systemic autoimmune disease does not affect overall survival in lung transplant
Data presented at ACR Convergence 2021 support the use of life-saving lung transplantation among qualified patients with systemic autoimmune diseases.
Breakthrough COVID-19 in vaccinated patients linked to B-cell therapies, mycophenolate
Among fully vaccinated individuals with rheumatic diseases, breakthrough COVID-19 infections occurred most commonly in patients treated with B cell depleting agents or mycophenolate, according to data presented at ACR Convergence 2021.
Majority of patients with RA maintain low disease activity on ultra-low dose rituximab
In an extension of the REDO trial, most patients with rheumatoid arthritis on ultra-low-dose rituximab — either 200 or 500 mg — maintained low disease activity for up to 4 years, according to data presented at ACR Convergence 2021.
Maintenance infliximab more effective with therapeutic drug monitoring
Therapeutic drug monitoring, in which serum levels are regularly checked to adjust dose and intervals, is more effective at controlling disease than standard therapy with infliximab, according to data presented at ACR Convergence 2021.
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