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JAK Inhibitors Video Perspectives

Healio spoke with expert rheumatologists about JAK inhibitors, including recent advancements, highlights from ACR, how to decide between JAK inhibitors for different patients, areas of future research and more.

Laura C. Cappelli, MD

In this video, Laura C. Cappelli, MD, assistant professor of medicine at Johns Hopkins University School of Medicine, discussed:

  • recent advances in rheumatoid arthritis treatment, including FDA approval of two JAK inhibitors: baricitinib (Olumiant; Eli Lilly) and upadacitinib (Rinvoq; AbbVie);
  • exercise and mindfulness as adjuncts to therapy in RA;
  • the importance of taking care of patients’ comorbidities and any side effects from RA medication;
  • differences between JAK inhibitors and biologics;
  • safety concerns of JAK inhibitors;
  • making sure patients with long-standing RA have treatment options;
  • the efficacy of JAK inhibitors in dermatologic diseases, like psoriatic arthritis;
  • considerations for patients nonresponsive to RA treatment; and
  • the need for novel agents with different mechanisms of action and targeted treatments for RA, as well as the importance of nonmedication options as adjuncts to improve quality of life.