Polymyositis News

A panel of 19 pediatric rheumatologists and two exercise physiology and physical therapy professionals involved in a European initiative called the Single Hub and Access Point for Pediatric Rheumatology in Europe used evidence-based research to develop a plan for the assessment and management of juvenile dermatomyositis, according to a recently published report.

A higher risk for malignancy was found in patients with clinically amyopathic dermatomyositis compared to other patients with dermatomyositis, most of whom required more than one treatment after diagnosis, according to recently presented research.

Myositis autoantibodies, particularly anti-p155/140, certain clinical features and environmental exposures were associated with a chronic disease course compared to patients with juvenile idiopathic inflammatory myositis who had a monocyclic or polycyclic course of disease, according to recently published research.

Patients with myositis who had positive anti-Jo-1 antibody status had higher serum levels of visfatin linked to higher clinical muscle involvement based on a VAS, according to recently published research.

Patients with myositis who tested positive for anti-Jo-1 antibodies had more severe muscle and lung involvement compared to patients with anti-PM-Scl antibodies, according to the results of a study conducted by Johns Hopkins University School of Medicine researchers.

Recently presented research showed MRI may be a helpful tool for monitoring disease activity in patients with polymyositis and dermatomyositis, particularly when patients have a normal creatine kinase level at baseline.

Although the use of interventional and diagnostic musculoskeletal ultrasound has increased among many providers, according to researchers from the University of Florida, the value of added testing is unclear.

Compared with a healthy control group, patients with either polymyositis or dermatomyositis had altered fatty acid profiles, which may represent a potential therapeutic target, according to a recent presentation by researchers from Stockholm University.

The American College of Rheumatology Annual Meeting in San Francisco begins on Nov. 7, and Healio Rheumatology will cover the event and its many topics — ranging from rheumatoid arthritis to spondyloarthropathies, osteoarthritis, systemic lupus erythematosus, scleroderma, vasculitis, fibromyalgia, juvenile arthritis and much more— throughout the week.

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