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June 16, 2021
29 min listen
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A Sickness in the Serum, Part 1: Serum Sickness and the Rheumatologist

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This episode delves into the clinical presentation of serum sickness along with a dash of Arthus reaction, to boot!

Brought to you by GSK.

  • Intro :10
  • Today’s episode :26
  • Let’s get into some cases 4:11
  • The Arthus reaction 6:06
  • What is another example of the same thing happening but on a systemic level? 7:25
  • Breaking down the clinical features of serum sickness 14:20
  • How confident are we that the compliment levels always drop? 16:26
  • How common is serum sickness? 19:45
  • The mechanistics of rituximab 21:36
  • A preview of parts two and three 27:37
  • Episode wrap-up 28:38

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Bayer G, et al. Eur J Intern Med. 2019;67:59-64.

Karmacharya P, et al. Semin Arthritis Rheum. 2015;35-334-340.

Lawley TJ, et al. J Invest Dermatol. 1985;85:129s-132s.

Sources/Disclosures

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Disclosures: Brown reports no relevant financial disclosures.