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Osteoarthritis and Bone Disorders News
No differences in knee morphology for older patients with vs without patellofemoral pain
Contradictory to current perceptions, older people with vs. without patellofemoral pain do not demonstrate differences in patellofemoral morphology on 3-D quantitative imaging analysis, according to findings.
Romosozumab followed by denosumab decreases fracture risk in postmenopausal women
The risks for new vertebral, clinical and nonvertebral fractures were reduced and bone mineral density increased in postmenopausal women assigned romosozumab followed by denosumab, according to results from the FRAME extension study presented at the American Society for Bone and Mineral Research Annual Meeting.
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HbA1c levels, diabetes duration linked to fracture risk
Adults with type 2 diabetes and obesity are at increased risk for any fracture, major osteoporotic fractures and hip fractures with longer duration of diabetes and higher HbA1c levels vs. those with shorter duration and lower levels, study data show.
Physical activity did not change 6 months after total hip or knee arthroplasty
There was no significant change in physical activity 6 months after total knee or hip joint replacement surgery, despite improvements in quality of life, pain and physical function, according to published results.
Burden of arthritis expected to increase among Australians
A population-level study for Australia, projected an increased prevalence of osteoarthritis and rheumatoid arthritis and health care costs related to these conditions.
‘Osteogenomic profile’ offers personalized fracture risk assessment
Bone mineral density-associated genetic variants may predict lifetime fracture risk for men and women, study data show.
Romosozumab followed by alendronate lowered risk for fracture in women with osteoporosis
There was a significantly lower risk for fracture seen among postmenopausal women with osteoporosis who received romosozumab followed by alendronate compared with women who received alendronate alone, according to recently published results.
Gene variants newly linked to osteoporosis, one is potential candidate for treatment drug target
A link between the loss of bone mineral density that can result in osteoporosis-related fractures and 153 new gene variants was found in a genome-wide association study of 142,487 individuals conducted by investigators at The University of Queensland and McGill University in Canada.
Bioventus receives FDA approval for hyaluronic acid injectable knee OA product
Bioventus announced it has received FDA approval for Durolane, a single-injection hyaluronic acid product for joint lubrication in the treatment of pain associated with knee osteoarthritis.
Study: Musculoskeletal ultrasound is increasingly taught in US rheumatology fellowships
A significantly greater number of rheumatology fellowships in the United States teach musculoskeletal ultrasound, according to recent findings.