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Osteoarthritis and Bone Disorders News
FRAX: A nuanced tool for predicting fracture risk
According to WHO, chronic noncommunicable diseases pose a significant threat to global public health and currently account for 70% of deaths worldwide. In the 1990s, as part of an increased focus on the burden of noncommunicable diseases, WHO identified osteoporosis as a future major health problem. To address this problem, researchers sought to create a tool designed to predict those at future risk for fragility fracture.
Physical activity low among older adults with, without knee OA
Older patients with symptomatic knee osteoarthritis had similarly low levels of moderate-to-vigorous physical activity as their peers who did not have knee pain or osteoarthritis, according to findings published in Arthritis Care and Research.
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Bioventus announces agreement to continue distribution of five-injection HA product for knee OA
Bioventus announced it has extended its agreement with Seikagaku Corporation to continue distributing the five-injection, hyaluronic acid product Supartz FX in the United States until May 2028.
As obesity-related health costs rise, experts warn of far-reaching complications
Obesity-related health care costs in the United States rose 29% between 2001 and 2015, and new data from the most populous states reveal that the cost burden varies throughout the country, according to research published in Clinical Chemistry.
Cutoff values for symptom state acceptability vary widely in patients with OA
Patient Acceptable Symptom State values do not appear consistent across dimensions and rheumatic conditions, suggesting that their use among patients with osteoarthritis and other rheumatic diseases may not be justifiable, according to findings published in the Journal of Rheumatology.
Positive results seen with autologous protein solution kit for treatment of knee OA
Zimmer Biomet Holdings Inc. announced that researchers of a pilot study have published positive results that demonstrate the nStride autologous protein solution kit as safe and efficacious for the treatment of knee osteoarthritis.
Teriparatide therapy beneficial in pregnancy- and lactation-induced osteoporosis
Women with pregnancy- and lactation-induced osteoporosis who experienced multiple vertebral fractures saw a 15% improvement in bone mineral density at the lumbar spine after 1 year of daily teriparatide therapy, as well as improvements in bone turnover markers vs. similar women who declined the drug, study data show.
Black patients lose 72,000 QALYs due to total knee replacement disparities
Racial disparities in the rates of total knee replacement among patients with osteoarthritis have resulted in blacks losing the equivalent of 72,000 quality-adjusted life years, according to findings published in Arthritis Care and Research.
Teriparatide reduces fracture risk in women with severe osteoporosis
Postmenopausal women with severe osteoporosis may have a lower risk for new vertebral fractures when treated with the anabolic agent teriparatide compared with risedronate, an antiresorptive therapy, study data show.
FDA grants fast track designation to CNTX-4975 injection for osteoarthritis knee pain
The FDA granted fast track designation to a synthetic, ultra-pure injection of trans-capsaicin for the treatment of pain linked with knee osteoarthritis, according to the drug’s manufacturer.