Osteoarthritis and Bone Disorders News

Reproductive and hormonal factors, such as pregnancy, increasing number of offspring and hormone replacement therapy use, are associated with increased knee osteoarthritis risk, according to findings published in Arthritis and Rheumatology.

Worse levels of knee pain, younger age and less severe structural damage are reliable predictors of which patients with osteoarthritis would benefit most from intra-articular hyaluronic acid injections, according to findings published in Arthritis Research and Therapy.

Geniculate artery embolization resulted in significant knee-osteoarthritis pain reduction and improvements in patients’ range of motion, according to interim results presented at the 2018 Society of Interventional Radiology annual meeting in Los Angeles.

Adults with type 2 diabetes who lost at least 30% of their maximum body weight had increased risks for fragility fractures and any fracture compared with those who lost less weight, according to findings published in Diabetes Care.

Women on bisphosphonates for at least 3 years who took a drug holiday for at least 12 months do not appear to have an increased risk for any osteoporosis-related fracture compared with women who persistently used bisphosphonates and those who were not adherent to persistent use, study data show.

Gene expression analysis of synovial tissue from patients with rheumatoid arthritis and osteoarthritis revealed three distinct synovial subtypes, and demonstrated that mechanisms of pain may differ among patients with different subtypes, according to findings published in Arthritis and Rheumatology.

MiMedx Group Inc. announced the FDA has granted the regenerative medicine advanced therapy designation to the company’s AmnioFix Injectable for use in the treatment of osteoarthritis of the knee.

Adults with pre-sarcopenia or sarcopenia are no more likely to sustain a fracture than adults with osteoporosis without sarcopenia, according to findings published in the Journal of Bone and Mineral Research.

There are no advantages to opioid medications compared with nonopioids in treating hip or knee osteoarthritis or severe chronic back pain at 12 months, according to findings published in the Journal of the American Medical Association.

More than half of knees that have no or mild radiographic osteoarthritis prior to knee replacement later go on to develop the disease during the following 4 years, according to findings published in Arthritis Care and Research.