Osteoarthritis and Bone Disorders News

Every 2 minutes, someone in the United States breaks their hip, and if that fracture is related to osteoporosis, the likelihood that person will experience another fracture jumps three to five times, according to the National Bone Health Alliance.

Arthroscopy for knee osteoarthritis offered no benefit in reducing or delaying the need for total knee arthroplasty compared with conservative treatment, according to a recently published study.

LIVERPOOL, England — Patients with knee osteoarthritis treated with a novel, intra-articular Wnt pathway inhibitor had significant improvements in symptomatic and medial joint space width compared to patients treated with placebo, according to results presented at the OARSI 2018 World Congress on Osteoarthritis.

LIVERPOOL, England — Novel recombinant human fibroblast growth factor-18 sprifermin was associated with ongoing treatment effect at 3 years in individuals with knee OA, according to findings presented here.

BOSTON — The potential rheumatic side effects of checkpoint inhibitor therapy in patients with cancer can include arthralgia, arthritis, polymyalgia rheumatica, giant cell arteritis, myositis, sicca syndrome and systemic lupus erythematosus, and can be chronic in approximately 50% of patients, according to findings presented here.

LIVERPOOL, England — Researchers identified six biomarkers in the synovial fluid of patients with OA that may be useful in stratification by risk or phenotype, according to findings presented here.

LIVERPOOL, England — Women with a lower baseline step rate were more likely than those with a higher step rate to experience cartilage damage worsening in the lateral patellofemoral and tibiofemoral joints at 2 years, according to findings presented here.

LIVERPOOL, England — A novel intra-articular injection of allogeneic gene-modified cell therapy was associated with significant improvements in International Knee Documentation Committee scores compared with placebo, according to findings presented here.

LIVERPOOL, England — An integrated care model marked by regular communication between general practitioners, orthopedic surgeons, and physical therapists yielded improved patient outcomes in a cohort of Norwegian patients, according to findings presented here.

LIVERPOOL, England — Despite failing to meet the primary numeric rating scale pain endpoint, MIV-711, a novel cathepsin K inhibitor, demonstrated joint protection in patients with knee OA, according to findings presented here.