Osteoarthritis and Bone Disorders News

Easily acquired data — such as education, depression symptoms, strenuous activity and obesity — can help identify functional decline risk among individuals before they develop osteoarthritis, according to a study published in the Annals of the Rheumatic Diseases.

Among patients with knee osteoarthritis, higher intake with both vitamins C and D is associated with less cartilage degeneration, while supplementation with vitamin D alone over 4 years is linked with significantly less progression of knee joint abnormalities, according to data published in Arthritis Care & Research.

Personalized Stem Cells Inc. announced it has received FDA approval for an investigational new drug application for the use of adipose-derived stem cells for the treatment of osteoarthritis.

Although black adults with knee osteoarthritis demonstrate worse performance-based physical function than white patients, these disparities are diminished when adjusting for socioeconomic and physical health factors, according to findings published in Arthritis Care & Research.

More than 25% of early-middle-aged adults had osteopenia in their neck, according to findings recently published in the Journal of the American Osteopathic Association.

Long-term bisphosphonate users who switched to the human monoclonal antibody denosumab experienced a gain in hip bone mineral density in the first year of therapy, whereas patients who switched to teriparatide experienced a transient loss in hip BMD, suggesting clinicians should exercise caution when changing osteoporosis agents for patients at high risk for hip fracture, according to a real-world analysis of electronic medical records.

Fasinumab, a recombinant, fully-human anti-nerve-growth-factor antibody, improved pain and physical function in patients with osteoarthritis, at various dose levels, even among individuals who experienced little benefit from previous analgesic therapy, according to recent findings in Arthritis & Rheumatology.

Individuals with osteoarthritis have a 2.5-times greater risk for having three or more other chronic conditions, including stroke and peptic ulcers, compared with those without osteoarthritis, according to findings published in Arthritis Care & Research.

Physiotherapists reported only moderate confidence in assessing fall risk and providing fall-prevention care for patients with osteoarthritis, and although asking such patients about their history of falls is common, physiotherapists rarely use screening tools or specific balance tests, according to survey results published in Arthritis Care & Research.

Metformin use was linked to a reduced rate of medial cartilage loss that may, in turn, reduce the risk for total knee replacement among patients with osteoarthritis who are obese, according to data published in Arthritis Research & Therapy.