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Osteoarthritis and Bone Disorders News
Clinicians have 'a ways to go' in managing osteoporosis in women
![Clinicians have 'a ways to go' in managing osteoporosis in women](/~/media/slack-news/rheumatology/mugs/m/mcclung_michael_2020.jpg?w=80)
Women with osteoporosis are not being identified and treated at sufficient rates, according to a presenter at the 2020 Congress of Clinical Rheumatology-West.
Targeting bone marrow lesions may reduce osteoarthritis pain
![Targeting bone marrow lesions may reduce osteoarthritis pain](/~/media/slack-news/rheumatology/mugs/m/malfait_annemarie_2020.jpg?w=80)
Research linking fluctuations in bone marrow lesions with pain fluctuations may suggest that targeting these lesions could successfully reduce osteoarthritis pain, according to a speaker at the 2020 Congress of Clinical Rheumatology-West.
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Distinct pain sensitization mechanisms dictate constant vs. intermittent pain in knee OA
![Distinct pain sensitization mechanisms dictate constant vs. intermittent pain in knee OA](/~/media/slack-news/rheumatology/mugs/c/carlesso_lisa_2020.jpg?w=80)
Among patients with, or at risk for, knee osteoarthritis, knee pain patterns could potentially be linked to peripheral ascending pain mechanisms and descending modulatory mechanisms, according to data published in Arthritis Care & Research.
Higher doses of tanezumab linked to abnormal peripheral sensation vs. NSAIDs in OA
![Higher doses of tanezumab linked to abnormal peripheral sensation vs. NSAIDs in OA](/~/media/slack-news/rheumatology/mugs/b/brown_mark_t_2020.jpg?w=80)
Among patients with osteoarthritis, increased tanezumab doses are associated with a higher incidence of abnormal peripheral sensation compared with NSAIDs, according to a speaker at the 2020 American Neurological Association Annual Meeting.
High-intensity physical activity through adolescence helps prevent osteoporosis
![High-intensity physical activity through adolescence helps prevent osteoporosis](/~/media/slack-news/rheumatology/mugs/e/elhakeem_ahmed_2020.jpg?w=80)
High-intensity physical activity throughout early life can help prevent osteoporosis and maximize peak hip strength later, according to data published in JAMA Network Open.
Despite 'great strides' in osteoporosis, questions remain
![Despite 'great strides' in osteoporosis, questions remain](/~/media/slack-news/rheumatology/mugs/l/lane_nancy80x106.jpg?w=80)
Novel therapies are providing hope in osteoporosis, but questions surrounding optimal treatment regimens remain, according to a presenter at the 2020 Congress of Clinical Rheumatology-East.
Turmeric extract eases knee pain in randomized trial
![Turmeric extract eases knee pain in randomized trial](/~/media/slack-news/stock-images/fm_im/t/tumeric_adobe.jpg?w=400)
An extract made from Curcuma longa, commonly known as turmeric, outperformed placebo for the treatment of osteoarthritis-related knee pain in older adults but had no significant impact on knee effusion-synovitis or cartilage composition, data showed.
Clinicians have 'reason for optimism' in novel osteoarthritis therapies
![Clinicians have 'reason for optimism' in novel osteoarthritis therapies](/~/media/slack-news/rheumatology/mugs/l/lane_nancy80x106.jpg?w=80)
A number of compounds and therapeutic approaches moving through the pipeline may soon enrich treatment paradigms for osteoarthritis, according to a presenter at the 2020 Congress of Clinical Rheumatology-East.
Canakinumab may reduce total knee, hip replacement, OA symptoms
![Canakinumab may reduce total knee, hip replacement, OA symptoms](/~/media/slack-news/rheumatology/mugs/c/conaghan80x106.jpg?w=80)
Interleukin-1 inhibition with canakinumab may substantially reduce rates of total hip and knee replacement, as well as osteoarthritis symptoms, according to data published in the Annals of Internal Medicine.
Patients with OA prefer therapy focus on disease progression with benefit to pain, walking
![Patients with OA prefer therapy focus on disease progression with benefit to pain, walking](/~/media/slack-news/stock-images/rheumatology/rheum-images/treadmill_running_twitter.jpg?w=400)
When presented with a range of treatment options, patients with osteoarthritis reported that the most important outcomes are disease progression and improving pain and walking, noted researchers in Seminars in Arthritis and Rheumatism.
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