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Lupus News
Renal arteriosclerosis accelerated, premature in lupus nephritis
Renal arteriosclerosis is both accelerated and premature among patients with lupus nephritis by 2 decades, compared with healthy peers, according to data published in Arthritis Care & Research.
Neuropsychiatric events most frequent near SLE diagnosis, linked to excess mortality
Among patients with systemic lupus erythematosus, neuropsychiatric events occur most frequently around the time of the initial diagnosis, and are associated with reduced health-related quality of life and excess mortality, according to data published in the Annals of the Rheumatic Diseases.
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Mental distress highly prevalent among adults with arthritis in Appalachia, southern US
Frequent mental distress is commonly reported among adults with arthritis across all 50 states and Washington, D.C., with the highest prevalence reported in the Appalachian region and southern states, according to data published in Morbidity and Mortality Weekly Report.
TULIP-2: Anifrolumab meets BICLA endpoint, confers higher skin response rates in SLE
Patients with systemic lupus erythematosus had a higher rate of British Isles Lupus Assessment Group-based Composite Lupus Assessment, or BICLA, response with anifrolumab compared with placebo, according to data from the TULIP-2 study, published in The New England Journal of Medicine.
Glucocorticoids linked to organ damage in SLE independent of disease activity
Glucocorticoid treatments contribute to organ damage accrual in patients with systemic lupus erythematosus, independent of clinical or serological disease activity, according to data published in The Lancet Rheumatology.
Ustekinumab beneficial through 1 year in SLE
Ustekinumab provides sustained clinical benefits through 1 year among patients with systemic lupus erythematosus, with a safety profile similar with its other indications, according to data published in Arthritis & Rheumatology.
Newly diagnosed cases of SLE at 62% increased risk for hip fracture
Patients newly diagnosed with systemic lupus erythematosus demonstrate a 62% increased risk for hip fractures compared with those without lupus, according to data published in Arthritis Care & Research.
Celebrating the life of Calvin R. Brown, Jr., MD, rheumatologist and teacher
The rheumatology community lost clinician and educator Calvin R. Brown, MD, on Dec. 1, 2019. He was 66 years old. His final years were spent at the Northwestern University Feinberg School of Medicine, practicing rheumatology and training fellows in the specialty.
9/11 first responders at increased risk for systemic autoimmune disease
Intense dust cloud inhalation, as well as PTSD, experienced by first responders and community members present at the Sept. 11 terrorist attack in New York are associated with a significant increased risk for systemic autoimmune disease, including rheumatoid arthritis and lupus, according to findings published in Arthritis & Rheumatology.
Health officials issue safety alert on unapproved stem cell products after Nebraska outbreak
Officials from the Nebraska Department of Health and Human Services have issued a public health advisory following multiple reports of serious adverse events in patients who were treated with unapproved stem cell products, particularly those marketed as containing exosomes.