Lupus News

Patients with rheumatic diseases who were pregnant at the time of developing COVID-19 demonstrated favorable pregnancy and infection outcomes, according to data published in The Journal of Rheumatology.

For children and adolescents initiating dialysis, lupus nephritis conferred a higher hospitalization risk, as well as a lower likelihood of transplantation, compared with other glomerular causes of end-stage kidney disease.

Updated evidence “strongly supports” ending the use of hydroxychloroquine for either preventing or treating COVID-19, due to a lack of benefits combined with potentially fatal cardiovascular complications, according to a meta-analysis.

The NIH has launched a clinical trial to examine antibody responses to a COVID-19 vaccine booster dose in patients with autoimmune disease who failed to respond to the initial vaccine regimen.

The presence of mature red blood cells that still contain mitochondria is associated with higher systemic lupus erythematosus disease activity, according to data published in Cell.

Among patients with arthritis, receiving exercise recommendations from a physician is “critical” to meeting physical activity guidelines and relieving symptom burden, regardless of race and ethnicity, researchers noted in BMC Public Health.

Patients with PTSD demonstrated a two-fold higher likelihood of being diagnosed with systemic lupus erythematosus, compared to those without PTSD, according to data published in Arthritis Care & Research.

About 29% of patients with systemic lupus erythematosus demonstrate low response to the COVID-19 vaccine, with immunosuppression therapy associated with decreased protection, according to data published in Arthritis & Rheumatology.

Although immunosuppressives remain the cornerstone for managing underlying interstitial lung disease in connective tissue diseases, new drug approvals could help shift the treatment paradigm, according to data presented here.

Cancer screening recommendations for patients with autoimmune diseases largely rely on clinical experience and extrapolation in the absence of abundant data, according to a speaker at the 2021 Congress of Clinical Rheumatology-East meeting.