Lupus News

Hispanic patients with systemic sclerosis are more likely to have concurrent systemic lupus erythematosus and U1-RNP positivity, and face greater mortality rates vs. non-Hispanic white patients, according to data.

Depression and physical function should be assessed at least once per year in all patients with systemic lupus erythematosus, according to recommended quality measures devised by an American College of Rheumatology workgroup.

Chimeric antigen receptor T-cell therapy produced persistent, drug-free remission in patients with one of three different B-cell autoimmune diseases, researchers reported at ASH Annual Meeting and Exhibition.

Fatigue in patients with inflammatory rheumatic and musculoskeletal diseases should be addressed with tailored physical activity, psychoeducational interventions or possibly immunomodulatory treatment, according to EULAR recommendations.

This month’s cover story analyzes a serious problem, namely the underrepresentation of patients from marginalized communities in lupus clinical trials.

The body of data demonstrating that lupus significantly and disproportionately impacts Black, Hispanic and Asian patients is robust. It should therefore follow that these populations are appropriately represented in clinical trials for the disease.

Black patients have a three- to five-fold increased incidence of primary chronic cutaneous lupus vs. white patients, but are often completely missing from training materials and most images of cutaneous lupus rashes online.

Poverty and chronic inflammation together may have a “synergistic” impact leading to higher all-cause mortality, including a 127% increased heart disease mortality risk and a 196% higher risk for cancer mortality, according to data.

Economic insecurities are “highly prevalent” among patients with systemic lupus erythematosus, and those with more insecurities demonstrate worse self-reported outcomes regardless of poverty or education, according to data.

Move over, Marc Maron. Step aside, Sharon Says So. Make way for Adam Brown, MD, of the Cleveland Clinic, host of the “Healio Rheuminations” podcast.