VIDEO: ‘Practice affirming’ findings from split-dosing methotrexate study at ACR

ByJeffrey A. Sparks, MD, MMSc

ByMarley V. Ghizzone

Fact checked byShenaz Bagha

SAN DIEGO — In this video, Healio spoke with Jeffrey A. Sparks, MD, MMSc, results from a study conducted in India assessing the efficacy of treating rheumatoid arthritis with split-doses of methotrexate.

The findings were presented at ACR Convergence 2023.

“This is practice affirming,” said Sparks, associate professor of medicine at Harvard Medical School and associate program director of the Rheumatology Fellowship, director of Immuno-Oncology and Autoimmunity and director of the Joint Biology Consortium Human Biosamples Core at Brigham and Women’s Hospital. “It really re-emphasizes that we should split the dose of methotrexate on the day that we give that each week.”

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Sources/Disclosures

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Source:

Dhir V, et al. Abstract 1583. Presented at: ACR Convergence 2023; Nov. 10-15, 2023; San Diego.

Disclosures: Sparks reports being supported by the Llura Gund Award funded by the Gordon and Llura Gund Foundation, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant numbers R01 AR080659, R01 AR077607, P30 AR070253, and P30 AR072577) and the R. Bruce and Joan M. Mickey Research Scholar Fund; receiving research support from Bristol Myers Squibb; and serving as a consultant for AbbVie, Amgen, Boehringer Ingelheim, Bristol Myers Squibb, Gilead Sciences, Inova Diagnostics, Janssen, Optum, Pfizer, ReCor, Sobi and UCB.

Discoveries in Rheumatoid Arthritis

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VIDEO: ‘Practice affirming’ findings from split-dosing methotrexate study at ACR

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