June 28, 2017
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Biologics more often led to remission in PsA vs conventional drugs

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Among patients with psoriatic arthritis, biologics more often led to remission or minimal disease activity compared with conventional drugs, according to a published analysis.

“The aim of our study was to evaluate the remission or [minimal disease activity] in a group of patients with [psoriatic arthritis] consecutively in an outpatient clinic and regardless of the treatment strategy by using the composite indices validated and tailored for [psoriatic arthritis],” researchers wrote.

Investigators assessed 109 patients with psoriatic arthritis (PsA), 79 who were treated with biologics and 30 with conventional drugs. In total, 25.6% of patients were in clinical disease activity index for PsA (cDAPSA) remission, 21.1% were in DAPSA remission, 17.4% had minimal disease activity (MDA) 7/7 and 11.9% had a PsA disease score (PASDAS) of 1.9 or less. In addition, 49.5% had MDA 5/7, 73.3% had DAPSA low disease activity (LDA), 72.3% had cDAPSA LDA and 34.8% had PASDAS LDA. Furthermore, patients on biologics had a significantly reduced median DAPSA, cDAPSA, and PASDAS compared with those treated with conventional drugs, the researchers wrote. – by Will A. Offit

Disclosures: The researchers report no relevant financial disclosures.