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5 Highly Accessed SLE Stories Include Microbiome, Role of Cytokines
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Recently presented research about systemic lupus erythematosus and cutaneous lupus have explored the role of the human gut microbiome, inflammatory cytokines and the potential of a new glucocorticoid-sparing agent.
Videos are available from Healio.com/Rheumatology’s live coverage of “Basic and Clinical Immunology for the Busy Clinician and Advances in Biologic Therapies Symposium: An Immunology Boot Camp,” which was sponsored by the Cleveland Clinic and held in Hollywood, Fla.
VIDEO: Silverman discusses human microbiome and lupus
HOLLYWOOD, Fla. — Gregg J. Silverman, MD, associate director of the Division of Rheumatology and professor in the Department of Medicine and Department of Pathology Medicine at the New York University School of Medicine spoke with Healio.com/Rheumatology about the human gut microbiome and its potential role in systemic lupus erythematosus (SLE) and autoimmune disease. Click to view.
VIDEO: Rigby discusses the role of complement in inflammation
HOLLYWOOD, Fla. — William Rigby, MD, vice-chair of the Department of Medicine and professor of medicine and microbiology at the Geisel School of Medicine at Dartmouth in Lebanon, N.H., discussed complement activity in relation to inflammation in autoimmune diseases. Click to view.
Potential steroid-sparing treatment enters SLE, IgG4-RD phase 2 trials
Xencor Inc. announced dosing of the first patient in a phase 2 trial of XmAb5871 to potentially treat patients with SLE. Read more.
Researchers identify cytokines in pathogenesis of cutaneous lupus erythematosus
Recently presented research suggests the cytokines interleukin-1, interleukin-17 and tumor necrosis factor-alpha are involved in the pathogenesis of cutaneous lupus erythematosus subtypes at the epidermis and dermis. Read more.
Patients with SLE, multiple CT scans may have a higher risk for malignancy
Patients with SLE with chest pain may undergo multiple CT scans for pulmonary embolism, and while multiple scans were associated with a lower likelihood of positive results and a higher risk for malignancy, researchers suggest the magnitude of risk should not discourage the use of CT when clinically indicated. Read more.