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Pulmonary Vascular Disease News
Benefit of upfront combination therapy not seen in low-risk PAH
Upfront combination therapy for patients with low-risk pulmonary arterial hypertension was not significantly better than monotherapy when assessing time to clinical worsening, according to results published in CHEST.
E-cigarette use lowers lung function, heightens blood pressure, heart rate
Following 15-minute use of an electronic nicotine delivery system, or ENDS, lung function fell and blood pressure and heart rate rose in long-term users vs. nonusers, according to results published in CHEST.
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Short-term JAK inhibitor therapy does not significantly increase serious adverse events
Janus kinase inhibitor therapy in short durations did not significantly increase the risk for major adverse cardiovascular events or venous thromboembolism in patients with low cardiovascular risk profiles, according to a study.
Major cancer surgery associated with ‘elevated’ risk for venous thromboembolism
Patients who underwent cancer surgery had an increased risk for venous thromboembolism for up to 1 year after the procedure, results from a retrospective study published in JAMA Network Open showed.
FDA has yet to confirm Yutrepia for pulmonary hypertension-ILD
The FDA did not meet its Prescription Drug User Fee Act goal date that would extend Yutrepia as a treatment for patients with pulmonary hypertension associated with interstitial lung disease, according to a press release.
Children with pulmonary embolism develop fewer long-term conditions than adults
Children who had a thromboembolic pulmonary embolism rarely developed post-PE syndrome, including high blood pressure in the lungs or cardiac or functional impairment, according to a study published in Blood.
‘Catastrophic’ PE associated with very high in-hospital mortality rate
The subset of patients with high-risk pulmonary embolism who had hemodynamic collapse had an in-hospital mortality rate of 42%, according to a retrospective analysis of a large registry.
Report: Sotatercept improves clinical outcomes in PAH, but unlikely to be cost-effective
When added to background therapy for pulmonary arterial hypertension, sotatercept improves 6-minute walk distance and WHO functional class vs. placebo, according to an evidence report by the Institute for Clinical and Economic Review.
Male patients, Black patients, rural residents more likely to die of pulmonary embolism
Male patients, Black patients and rural area residents with pulmonary embolism had poorer age-adjusted mortality rates than their respective opposing demographics, according to results published in Annals of the American Thoracic Society.
Catheter-directed thrombolysis for PE confers less bleeding vs. mechanical thrombectomy
SAN FRANCISCO — In the REAL-PE study of a real-world population of patients with pulmonary embolism, catheter-directed thrombolysis was associated with reduced risk for major bleeding compared with mechanical thrombectomy.
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Headline News
Burnout, withdrawal remain ‘alarmingly high’ among physicians and residents
September 17, 20242 min read -
Headline News
Over one-third of adults not planning on receiving recommended vaccines this fall
September 18, 20242 min read -
Headline News
Popular home BP devices unable to provide accurate readings for millions due to sizing
September 19, 20242 min read
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Headline News
Burnout, withdrawal remain ‘alarmingly high’ among physicians and residents
September 17, 20242 min read -
Headline News
Over one-third of adults not planning on receiving recommended vaccines this fall
September 18, 20242 min read -
Headline News
Popular home BP devices unable to provide accurate readings for millions due to sizing
September 19, 20242 min read