Pulmonary Vascular Disease News

DALLAS — Adding treprostinil to monotherapy, as compared with placebo, reduced the risk for clinical worsening events in patients with pulmonary artery hypertension, especially after adjustment for baseline risk, new data from FREEDOM EV indicate.

CLEVELAND — Every patient with systemic sclerosis should be screened for pulmonary arterial hypertension every year, as early recognition, referral and aggressive treatment are necessary to improve long-term outcomes, according to Virginia Steen, MD, of the Georgetown University Medical Center.

DALLAS — A dry powder formulation of treprostinil was safe and well tolerated at 2 months, with no drug-related serious adverse events, in patients with pulmonary arterial hypertension, according to new data from the phase 3 INSPIRE trial presented at the American Thoracic Society International Conference.

DALLAS — In a post hoc exploratory analysis of the GRIPHON study, treatment with selexipag, compared with placebo, improved clinical outcomes in patients with peripheral artery hypertension regardless of time from diagnosis to treatment initiation, with a more pronounced treatment effect in patients who received selexipag soon after diagnosis.

New data show that pulmonary arterhypertension diagnostic algorithms that have been developed using administrative health data differ significantly in design and predictive value.

NEW ORLEANS — Interim data from the REPAIR study show significant improvement in right ventricular function, including reversal of RV remodeling and reduced pulmonary vascular resistance, at 26 weeks after treatment with macitentan in patients with pulmonary artery hypertension.

The FDA has issued a safety alert regarding a clinical study that has found a 10-mg, twice-daily dose of tofacitinib increased the risk for pulmonary embolism and mortality in patients with rheumatoid arthritis.

Eight common chronic diseases accounted for more than one-fifth of incident cancer risk, according to prospective study results.

Participants exposed to dust clouds and injury on 9/11 were later diagnosed with respiratory and heart diseases, according to a study published in Injury Epidemiology.

Pulmonary embolism was associated with lupus, according to results of a recently published retrospective study.