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Pulmonary Vascular Disease News
Two studies provide further positive outcomes for empagliflozin in HF
Among patients with HF, empagliflozin lowered diastolic pulmonary artery pressure and was effective at reducing CV death and HF hospitalizations regardless of sacubitril/valsartan use, researchers reported.
Mixed results for levosimendan in HFpEF, pulmonary hypertension
In patients with HF with preserved ejection fraction and pulmonary hypertension, levosimendan did not meet its primary endpoint but met two secondary endpoints, according to results from the phase 2 HELP-PH-HFpEF trial.
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Top news of September: COVID-19 long-term follow-up, novel chronic cough therapy and more
The Healio editors have compiled a list of the most-read pulmonology news published in September.
Switching from PDE5 inhibitors to riociguat confers benefit in intermediate-risk PAH
Patients with pulmonary arterial hypertension at intermediate risk who switched from phosphodiesterase type 5 inhibitors to riociguat experienced clinical improvement at 24 weeks, according to results of the REPLACE study.
No treatment benefit with pirfenidone plus sildenafil for IPF, pulmonary hypertension
Combination therapy with pirfenidone plus sildenafil did not provide treatment benefit in patients with advanced idiopathic pulmonary fibrosis and risk for pulmonary hypertension compared with pirfenidone plus placebo.
Two triaging strategies equally safe for facilitating outpatient care of acute PE
New data from the HOME-PE trial support outpatient management of patients with acute pulmonary embolism using two different triaging strategies.
Top pulmonology news in August: COVID-19 and air quality, vitamin D for asthma and more
The Healio editors have compiled a list of the most-read pulmonology news published in August.
Pulmonary vascular dilation may cause hypoxemia in COVID-19-related pneumonia
Pulmonary vascular dilation appears to play a role in hypoxemia in patients with COVID-19-related pneumonia, researchers reported in a new study published in the American Journal of Respiratory and Critical Care Medicine.
Recent updates in pulmonary hypertension: New treatment options, inhaled therapy and more
The Healio editors have compiled a list of recent updates in the management and treatment of pulmonary hypertension.
Initial triple therapy vs. double may improve outcomes in newly diagnosed PAH: TRITON
In patients with newly diagnosed pulmonary arterial hypertension, initial triple oral therapy, compared with double therapy, both improved hemodynamics, NT-proBNP and functional capacity, with no difference between strategies at 26 weeks.