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Lung Cancer News
Proton therapy shows promise for recurrent lung cancer
Intensity-modulated proton therapy conferred durable control with minimal toxicity among patients with recurrent thoracic cancer, according to results of a retrospective study presented at the Multidisciplinary Thoracic Cancers Symposium.
Cancer surveillance guidelines lack specificity, consistency
Recommendations for surveillance after cancer treatment in survivors across guidelines are often nonspecific and inconsistent; therefore, clarification for or against the use of specific tests is warranted in current guidelines, according to findings published in JAMA Internal Medicine.
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Radiation prior to immune checkpoint inhibitor therapy may lower toxicity
Ten percent of patients with lung cancer who received thoracic radiation therapy with immune checkpoint inhibitors experienced severe toxicities, according to a retrospective study presented at the Multidisciplinary Thoracic Cancers Symposium.
Multiple biopsies may help identify, treat resistance in NSCLC
More than one in five patients with non–small cell lung cancer develop various types of genetic resistance during treatment and could benefit from additional biopsies to alter treatment, according to a study presented at the Multidisciplinary Thoracic Cancers Symposium.
Phase 1b trial of HS-110, nivolumab combination meets efficacy endpoint in NSCLC
The phase 1b trial designed to evaluate HS-110 in combination with nivolumab for the treatment of non–small cell lung cancer met its efficacy endpoint and will advance into a phase 2 trial, according to the drug’s manufacturer.
Lung cancer screening rates remain low among current, former smokers
Use of annual lung cancer screenings with low-dose CT remains low among current and former smokers following the 2013 recommendations by the U.S. Preventive Services Task Force, according to a research letter published in JAMA Oncology.
CMS plans to implement appropriate use mandate for imaging procedures in 2018
When ordering advanced imaging procedures, such as radionuclide imaging, MRI and CT, physicians will soon be required to consult appropriate use criteria using CMS-approved computer-based clinical decision support mechanisms, due to an impending provision by CMS in the Protecting Access to Medicare Act, according to a commentary published in Annals of Internal Medicine.
Early palliative care may improve quality of life in patients with lung, gastrointestinal cancers
Early integration of palliative care for patients with newly diagnosed incurable gastrointestinal and lung cancers improved quality of life, reduced depression symptoms, and enhanced coping with prognosis and communication about end-of-life preferences, according to a randomized clinical trial published in Journal of Clinical Oncology.
Oral contraceptives reduce risk for some cancers
The benefits of oral contraceptives outweigh the harms, protecting against lifetime risks of certain cancers, including endometrial, ovarian and colorectal cancer, according to research published in the American Journal of Obstetrics and Gynecology.
FDA grants priority review to Zykadia for ALK–positive metastatic NSCLC
The FDA granted priority review to a supplemental new drug application that seeks to expand the use of ceritinib to include first-line treatment of anaplastic lymphoma kinase–positive metastatic non–small cell lung cancer, according to the drug’s manufacturer.
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