Cystic Fibrosis News

In kids aged 6 years and older with cystic fibrosis and either F508del/minimal function or F508del/F508del genotypes, elexacaftor/tezacaftor/ivacaftor was safe and well tolerated for up to 120 weeks, according to study results.

Receipt of 4D-710, an aerosolized gene therapy, resulted in high cystic fibrosis transmembrane conductance regulator protein expression levels in patients with cystic fibrosis, according to a company press release.

For patients with cystic fibrosis, exercise helps with disease management, and exercise tests allow clinicians to assess lung health, muscle strength and treatment response, according to a press release from University of Portsmouth.

Among patients with cystic fibrosis, increases in sulfate and specific metals in water raised the odds for nontuberculosis mycobacterial infections, according to results published in Environmental Epidemiology.

Infants with cystic fibrosis who received care at 47 days old had decreased weight and height-for-age during infancy compared with infants who received care at 10 days old, according to results published in The Journal of Pediatrics.

Patients with cystic fibrosis had an average survival of 66 years in 2022, which is a notable increase from 26 years in 2008, according to study results from Epic Research.

Following newborn screening, a cystic fibrosis diagnosis is often delayed or missed in non-white infants, which can result in hospitalization and early life malnutrition, according to a Lurie Children’s Hospital press release.

WASHINGTON — Among healthy young adults, 28% had intermediate sweat chloride levels, with lung function measures similar to those with normal levels, according to a poster presented at the American Thoracic Society International Conference.

Texas Children's Hospital was named the top hospital for pediatric pulmonology and lung surgery in the 2023 to 2024 rankings by U.S. News & World Report.

WASHINGTON — For people with skin of color, a diagnosis of cystic fibrosis is often delayed or missed, and they are not well represented in treatment trials, according to an American Thoracic Society International Conference presentation.