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January 31, 2020
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Spotlight on critical care: Vitamin C for sepsis, trends in ICU outcomes

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Healio has compiled a list of recent articles highlighting news, research and issues in critical care medicine.

See below for links to the latest study on use of vitamin C for sepsis treatment, disparities in critical care deaths, data on ICU outcomes and more.

Adding vitamin C, thiamine to hydrocortisone fails to improve sepsis outcomes

When compared with hydrocortisone alone, treatment with a combination of IV vitamin C, thiamine and hydrocortisone did not prolong time alive and free of vasopressor administration for patients with septic shock, according to data from the VITAMINS trial. Read more

Hospital-based palliative care may reduce ICU use

The implementation of hospital-based palliative care services was associated with a modest decrease in ICU use during terminal hospitalizations in New York, according to a study published in JAMA Network Open. Read more

Disparity in critical care deaths persists in minority-serving hospitals

Hospitals that see fewer minority patients have experienced a downward trend in ICU deaths during the past decade, but the same has not been true for hospitals with larger minority populations, researchers reported in the American Journal of Respiratory and Critical Care Medicine. Read more

Healio has compiled a list of recent articles highlighting news, research and issues in critical care medicine.
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Mortality with two stress ulcer prophylaxis treatments did not differ in critically ill patients

Among critically ill patients requiring mechanical ventilation, 90-day in-hospital mortality rates did not differ significantly between those who received proton pump inhibitors and those who received histamine-2 receptor blockers for stress ulcer prophylaxis, new data published in JAMA indicate. Read more

Lung microbiome may predict ICU outcomes

New data suggest that important features of the lung microbiome may predict ventilator-free days among critically ill, mechanically ventilated patients. Read more