Schizophrenia News

Analysis of an observational study cohort showed an increased risk for diabetes among individuals with psychosis taking antipsychotics with no family history of diabetes, while those with a family history exhibited no additional risk for diabetes.

Individuals at ultra-high risk for psychosis and those with schizophrenia exhibited increased microglial activity compared with healthy controls, suggesting a link between neuroinflammation and psychosis.

Recent study findings show severity of unusual thought content, suspiciousness, reduced ideational richness and difficulty focusing or concentrating predicted risk for psychosis among individuals considered at high-risk for psychosis.

Stigma related to risk-label and symptoms of psychosis was associated with increased depression and anxiety among individuals at clinical high-risk for psychosis, suggesting stigma-related shame should be addressed in early interventions.

Results from a population-based cohort study indicate individuals with schizophrenia, particularly those aged younger than 65 years, had increased relative risk for dementia that was not explained by dementia risk factors.

The NIMH has awarded $3.5 million to fund the second phase of the Bipolar-Schizophrenia Network on Intermediate Phenotypes consortium, a multi-university collaboration focused on increasing development of novel therapies and creating a new system of diagnosis for psychotic disorders using biomarkers.

The FDA recently approved Aristada, an extended-release injection drug, to treat schizophrenia in adults, according to a press release.

Elevated myocardial infarction-associated transcript levels alter ErbB4 splicing in parvalbumin interneurons in schizophrenia, which may contribute to lower activity of parvalbumin interneurons and down-regulation of parvalbumin expression.

Cognitive behavioral therapy reduced insomnia among individuals with persistent delusions or hallucinations associated with insomnia and a schizophrenia spectrum diagnosis, according to study findings in Lancet Psychiatry.

The overall rate of emergency department visits related to schizophrenia for men was approximately double the rate for women, according to a data brief from the National Center for Health Statistics.