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Schizophrenia News
Atypical antipsychotics in first trimester may not increase risk for congenital defects
Analysis of a nationwide sample indicated exposure to atypical antipsychotics in the first trimester of pregnancy did not significantly increase risk for congenital malformations.
Alkermes submits sNDA for new dosage of Aristada for schizophrenia
Alkermes recently announced the submission of a supplemental New Drug Application to the FDA for a 2-month dosing interval of Aristada extended-release injectable suspension for schizophrenia.
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Vraylar ineffective as adjunct therapy for treatment-resistant MDD
Allergan and Gedeon Richter recently released findings that indicated inefficacy of flexible doses of Vraylar as adjunctive treatment for treatment-resistant major depressive disorder.
Antipsychotic polypharmacy common after discharge from inpatient psychiatric hospitals
Recent findings indicated antipsychotic polypharmacy among 12% of individuals discharged from a state psychiatric inpatient hospital.
Adjunctive raloxifene improves outcomes in women with refractory schizophrenia
Raloxifene hydrochloride, a selective estrogen receptor modulator with mixed agonist and antagonist activity, reduced illness severity and increased likelihood of clinical response in women with treatment-resistant schizophrenia, according to recent findings.
Data show accuracy of risk calculator for conversion to psychosis
Recent findings indicated accuracy of a risk calculator for individual risk for conversion to psychosis among clinical high-risk individuals.
Exposure to violence increases risk for violent crime regardless of psychiatric disorder
Exposure to violence increased risk for violent crime among individuals with and without psychotic disorders, and parental bereavement particularly increased risk for crime among those with schizophrenia.
Maternal thyroid deficiency during pregnancy increases risk for schizophrenia
Hypothyroxinemia during early to mid-gestation was associated with increased risk for schizophrenia in offspring, according to recent findings.
Adjunctive antidepressants safe, effective for depression in schizophrenia
Recent findings indicated antidepressants added to antipsychotics for schizophrenia had small, beneficial effects with low risk for exacerbation of psychosis and adverse effects.
Mortality risk higher among early, heavy cannabis users
Individuals with an early history of heavy cannabis use have higher risk for death than those with no history of cannabis use, according to recent findings.