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Schizophrenia News
FDA accepts NDA for RBP-7000 to treat schizophrenia
The FDA has accepted the New Drug Application for Indivior’s RBP-7000, a once-monthly, sustained release, injectable risperidone in the Atrigel delivery system, for the treatment of schizophrenia, according to a press release.
Impaired auditory stimuli inhibition linked to features of schizophrenia
Deficits in auditory stimuli inhibition are associated with core pathological features of schizophrenia, supporting the idea that P50 inhibitory processing may guide the development of that target impairments in schizophrenia, according to recent findings.
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Risk of developing psychosis varies by place, person
Results from a 17-site, international incidence study confirm marked heterogeneity in risk for psychotic disorders by person and place, such as higher rates in younger men, racial/ethnic minorities and areas characterized by a lower percentage of owner-occupied homes.
One-third of adults with substance-induced psychosis convert to schizophrenia, bipolar disorder
Recent findings indicated a strong association between substance-induced psychosis and conversion to schizophrenia and bipolar disorder, suggesting a need for long-term follow-up to identify most cases.
Psychotic symptoms may predict later hospitalization
Psychotic symptoms were associated with later hospitalization for nonaffective psychotic disorders among Israeli military members aged 18 to 21 years; however, symptoms had low predictive value.
Social environment may influence psychosis risk
Nonaffective psychoses were more common among individuals living in economically deprived and socially isolated rural areas, according to recent findings.
Digital avatar therapy improves verbal hallucinations in schizophrenia
Avatar therapy decreased the severity of persistent auditory verbal hallucinations among individuals with schizophrenia or affective disorders and was more effective than supportive counseling alone.
Study shows genetic risk gradient across schizophrenia, bipolar disorder
Recent findings indicated a polygenic risk gradient across schizophrenia and bipolar disorder, which was associated with the presence and severity of mood-incongruent psychotic symptoms.
FDA grants fast track designation to lumateperone for schizophrenia
Intra-Cellular Therapies Inc. recently announced the FDA granted fast track designation for lumateperone for treatment of schizophrenia.
FDA accepts NDA for Aristada dispersion product
The FDA recently accepted for filing a New Drug Application for aripiprazole lauroxil NanoCrystal Dispersion, an investigational product designed for initiation to Aristada extended-release injectable suspension, for treatment of schizophrenia, according to a release from Alkermes.
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