Schizophrenia News

Early exposure to urbanicity, migration, abuse and cannabis or alcohol during youth strongly predicted violent aggression in adulthood, data published in Molecular Psychiatry suggest.

Research findings published in Nature Medicine showed the most significant genetic variants linked to schizophrenia converge in the placenta; however, only certain variations in the genetic make-up may result in schizophrenia when there are complications during pregnancy.

Findings from the 2016 global burden of disease study indicated that population growth and aging has led to an increasing disease burden attributable to schizophrenia globally, especially in middle-income countries.

Contrary to established findings that urbanicity is a risk factor for psychotic disorders, newly published study results demonstrated that urban living may not be linked to a higher risk for psychosis in low- and middle-income countries.

NEW YORK — Women who continued antipsychotic treatment with olanzapine or quetiapine during pregnancy had an increased risk for gestational diabetes compared with those who discontinued treatment, according to data here and simultaneously published in The American Journal of Psychiatry.

NEW YORK — Women with a family history of mental illness, especially bipolar disorder, are at higher risk for postpartum psychiatric disorders, according to data released here and simultaneously published in The American Journal of Psychiatry.

NEW YORK — Discontinuing cariprazine treatment may be linked to delayed incidence of schizophrenia relapse compared with other oral atypical antipsychotics, according to poster data presented here.

NEW YORK — Phase 1 data demonstrated a nano-crystalline milled dispersion of aripiprazole lauroxil, an investigational product designed for initiation onto Aristada, was well-tolerated when combined with 30-mg oral aripiprazole as part of a 1-day initiation regimen, according to a Alkermes press release. Data will be presented in a poster here.

Findings from a meta-analysis published in JAMA Psychiatry showed that early intervention services were superior to treatment as usual across all meta-analyzable outcomes in early-phase psychosis.

Patients who later develop psychosis exhibited disorganized gyrification network properties, indicating that constructing gyrification-based networks may help predict future psychosis, even among those at high risk, according to study findings published in JAMA Psychiatry.