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Schizophrenia News
Accelerated functional brain network aging observed in psychosis
Patients with psychotic disorders had accelerated aging of two functional brain networks that support cognitive function — the frontoparietal network and cingulo-opercular network — according to a cross-sectional study published in Biological Psychiatry.
A clinical pharmacist’s guide to long-acting injectable antipsychotics
Long-acting injectable antipsychotics have been shown to prevent symptom relapse while addressing patient adherence. However, questions remain regarding their advantages and disadvantages, as well as which patients are appropriate candidates.
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Tobacco use linked to psychotic experiences in adolescence
Tobacco use appeared to be associated with psychotic experiences — such as paranoia and hallucinations — during adolescence, largely due to shared genetic influences, according to study findings.
Starting aripiprazole may not increase risk for psychiatric treatment failure
Compared with initiation of another antipsychotic drug, starting aripiprazole after prior antipsychotic exposure was not associated with psychiatric hospitalization, self-harm or suicide in a population-based cohort study.
Early-risers may have better mental health than night owls
Using Mendelian randomization, researchers found that being a morning person was causally associated with better mental health; however, it did not affect BMI or risk for diabetes.
B vitamins may benefit some patients with first-episode psychosis
Researchers found no overall benefit of adjuvant vitamin B12, B6 and folic acid on symptoms and neurocognition in first-episode psychosis, according to study findings.
Valbenazine shows sustained improvement in tardive dyskinesia
Once-daily treatment with valbenazine resulted in 6-week and sustained improvements in tardive dyskinesia in adults with a mood disorder, according to recent study findings.
Comorbidity within all mental disorders highly prevalent
In a Danish population-based cohort study of almost 6 million people, researchers found that individuals with any mental disorder were at increased risk for comorbid mental disorders.
People with, without severe mental illness may have similar social brain function
People with and without a schizophrenia spectrum disorder showed differing patterns of neural activity during a socio-emotional task, independent of DSM diagnosis, according to a multisite brain imaging study published in The American Journal of Psychiatry.
Repurposing commonly-used drugs may benefit those with serious mental illness
Exposure to hydroxylmethyl glutaryl coenzyme A reductase inhibitors, L-type calcium channel antagonists and biguanides may lead to improved outcomes for people with serious mental illnesses, according to study data.
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