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Schizophrenia News
Voice-analysis application assesses well-being of patients with serious mental illness
An interactive voice response system that uses artificial intelligence effectively monitored the well-being of patients with serious mental illness, according to study findings published in PLOS One.
Psychiatric patients significantly more likely to be perpetrators and victims of violence
Patients with psychiatric disorders are significantly more likely to be victimized by or perpetrators of violence than those without psychiatric disorders, according to findings of a nationwide cohort study published in JAMA Psychiatry.
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Study offers insights into trajectory of psychotic experiences from childhood to adulthood
An unmet need exists for care among young people with psychotic disorders, according to results of a population-based cohort study published in American Journal of Psychiatry. Researchers reported that incidence of psychotic experiences peaked during late adolescence.
BMI linked to major psychiatric disorders
Findings of a genome-wide association study published in JAMA Psychiatry suggest that many overlapping genetic risk variants exist between BMI and schizophrenia, bipolar disorder and major depression.
Lumateperone safe, effective for patients with schizophrenia
Results of a randomized clinical trial demonstrated a favorable safety profile and efficacy of lumateperone for patients with schizophrenia.
Prescribing antipsychotics at higher than 95% effective dose may not offer additional efficacy
Patients with chronic schizophrenia who have acute exacerbations may not experience increased benefit from receiving antipsychotic doses higher than the identified 95% effective doses, according to results of a meta-analysis published in American Journal of Psychiatry.
Polygenic scores can help determine schizophrenia subgroups
Schizophrenia subgroups with distinct cognitive development trajectories can be determined using adult cognitive data, according to study findings published in American Journal of Psychiatry. Researchers noted that these subgroups have significantly different profiles of cognitive, academic and psychiatric genetic influence.
FDA approves Caplyta for schizophrenia
The FDA has approved Caplyta for the treatment of schizophrenia in adults, according to a press release from the agent’s manufacturer.
Having dogs as pets may decrease schizophrenia risk
Individuals who were exposed to household pet dogs during infancy and childhood may have a decreased risk for developing schizophrenia, according to study findings published in PLoS One.
Q&A: Treatment potential of ALKS 3831 for schizophrenia, bipolar I disorder
Alkermes recently announced submission of a new drug application to the FDA for its investigational schizophrenia treatment ALKS 3831, a combination of olanzapine and samidorphan, for the treatment of schizophrenia and the treatment of bipolar I disorder. If approved, the drug is intended to provide the antipsychotic efficacy of olanzapine while mitigating olanzapine-associated weight gain.
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