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Obsessive-Compulsive Disorder News
Reward learning may offer novel therapeutic target in OCD
Using a sensory preconditioning paradigm to determine the extent to which individuals were using past experiences to guide their behavior, researchers found that those with obsessive-compulsive disorder were less likely to generalize from rewards than those with social anxiety disorder and healthy controls.
Error processing, inhibitory control both altered in OCD
After conducting a meta-analysis of data from functional MRI studies, researchers found that patients with obsessive-compulsive disorder showed hyperactivation in certain regions of the brain during error-processing and hypoactivation in other regions during inhibitory control when compared with healthy controls.
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Infections may increase risk for mental disorders, psychotropic use
Severe infections requiring hospitalization were linked to subsequent increased risk for hospitalization for any mental disorder and psychotropic medication use in Denmark, according to a nationwide cohort study published in JAMA Psychiatry.
VIDEO: CBT effective intervention in OCD
ORLANDO, Fla. — Cognitive behavioral therapy can be an effective intervention for individuals with obsessive-compulsive disorder, according to Eric Storch, PhD, professor in the department of psychiatry and behavioral sciences and McIngvale Presidential Endowed Chair at Baylor College of Medicine.
GeneSight genetic test yields cost savings for psychiatric patients
A health economic study evaluating the financial impact of the GeneSight combinatorial pharmacogenomic test on major commercial health plans found that use of the test yielded reduced spending for a commercial health plan among patients with psychiatric disorders.
FDA permits marketing of brain stimulation system for OCD
The FDA has permitted Brainways Ltd. to market the Brainsway Deep Transcranial Magnetic Stimulation System for the treatment of obsessive compulsive disorder, according to a press release.
Neuroscience themes inform treatment planning for OCD
Collectively understanding five neuroscience themes — phenomenology and symptom dimensions, extinction science, neurochemistry, genetics, and animal models and neurotherapeutics — is key to formulation and treatment planning for patients with obsessive-compulsive disorder, according to a review published in JAMA Psychiatry.
Heightened performance monitoring in early childhood linked to OCD
Findings published in JAMA Psychiatry showed that heightened performance monitoring evident in early childhood was associated with the onset of obsessive-compulsive disorder during adolescence and smaller right dorsal anterior cingulate cortex volume.
Antidepressants equally effective across severity levels of social anxiety, OCD, PTSD
Results from an individual patient data metaanalysis demonstrated that antidepressants are equally effective for all severity levels of social anxiety disorder, OCD and PTSD, but for generalized anxiety disorder and panic disorder, the benefits are small at low severity level.
Patients with OCD lack adaptive coping skills
Patients with obsessive compulsive disorder had more maladaptive coping skills and fewer adaptive coping skills than controls, according to research findings. In addition, insufficient adaptive coping skills in these patients were also strongly associated with resistance to symptoms and poor insight into the disorder.
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