Mood Disorders News

Research published in JAMA Psychiatry showed that children aged 6 to 12 years presenting with high irritability and depressive/anxious mood were twice as likely to have suicidal thoughts or attempt suicide in adolescence than children with low irritability and depressive/anxious mood.

Men and women with major depression have opposite molecular signatures in three corticolimbic brain regions, with multiple transcriptional changes in opposite directions, according to data published in Biological Psychiatry.

Playing violent video games every day for 2 months did not negatively affect aggression, impulsivity-related factors, mood, anxiety, empathy, interpersonal competencies or executive control in adults, according to research published in Molecular Psychiatry.

Although rates of opioid prescribing for adolescents are low, those with anxiety, mood and neurodevelopmental disorders, as well as those with other mental health conditions and treatments, are more likely to be prescribed any opioid.

Twenty-one commonly used antidepressant medications appeared more effective than placebo for the treatment of major depressive disorder in adults, according to findings from an international study.

Among American adults, the lifetime prevalence of DSM-5 major depressive disorder is more than 20%, and the disorder is associated with multiple comorbidities and impairments, according to nationally representative data published in JAMA Psychiatry.

The rate of all-cause mortality observed among adolescents and young adults after first diagnosis of psychotic disorder was about eight times higher than the rate observed among a matched control group of general outpatient service users, according to data published in JAMA Psychiatry.

Analysis of neuroimages showed that callous-unemotional traits are associated with the variations in brain structure of boys only, highlighting the importance of considering sex as a factor in child psychiatry.

Volume size of the left putamen was greater in older adult healthy controls compared with older adults with major depressive disorder, according to new study results.

Recent findings suggest that early-life adversities, such as war-related exposures, are associated with mental health disorders that affect several generations.