Geriatrics News

The NIH is funding a study that will explore predicting antidepressant response among individuals aged 60 years and older with depression, according to a press release.

Study findings in Neurology show that resveratrol penetrated the blood-brain barrier in individuals with Alzheimer’s disease to have central nervous system effects, providing class II evidence that resveratrol is safe, well-tolerated and affects some Alzheimer’s disease biomarkers.

Data from an international multicenter study indicated the central role calcium signaling plays in hippocampus-dependent human memory processes in cognitive health and disease, which may aid understanding and potential treatment of hippocampus-dependent cognitive pathology.

Cross-sectional analysis of the Alzheimer’s Disease Neuroimaging Initiative study cohort suggests type 2 diabetes may encourage neurodegeneration independent of Alzheimer’s disease dementia, and may be driven by tau phosphorylation.

Discontinuing antihypertensive medications did not improve cognitive, psychological or general daily functioning in elderly patients with mild cognitive defects, according to results from the DANTE Study Leiden.

Strong relationships with neighbors had a protective effect on risk for PTSD among older adults exposed to Hurricane Sandy, a destructive hurricane that affected the northeast United States in 2012.

In a meta-analysis of 323 studies, researchers identified medical, dietary, biochemical, psychological and lifestyle factors associated with increased and decreased risk for Alzheimer’s disease.

Individuals with higher depression severity were more likely to exhibit non-response trajectories to venlafaxine hydrochloride for late-life depression, according to study findings in JAMA Psychiatry.

A newly developed brief screening tool for dementia accurately staged the disease without extensive training or clinician input and showed comparable accuracy to the Clinical Dementia Rating.

Older individuals with dementia taking cholinesterase inhibitors were more likely to experience 10-pound weight loss after 12 months than peers taking other medications, according to study findings in the Journal of the American Geriatrics Society.