Geriatrics News

A phase 2 trial showed that Nuplazid significantly improved certain psychosis scores at 6 weeks in patients with severe psychosis related to Alzheimer’s disease, according to findings recently published in Lancet Neurology.

Study findings indicated that cognitively healthy people aged 85 to 94 years with increased cholesterol levels at midlife were less likely to experience marked cognitive decline over the next decade compared with those aged 75 to 84 years who also had elevated cholesterol levels at midlife.

A prospective study of middle-aged and elderly twins in Denmark showed no association between long-term use of proton pump inhibitors and cognitive decline.

Asymptomatic people with a family history of sporadic Alzheimer’s disease were more likely to show abnormal cerebrospinal fluid and brain amyloid- biomarkers as they neared their parent’s onset age, indicating that proximity to parental symptom onset may help predict amyloid- biomarker changes, according to study findings.

Dementia is becoming an increasingly important health problem in the United States, but primary care providers may be lacking understanding of guidelines and pharmacologic treatment options based on results of a survey published in a recent issue of the Journal of the American Board of Family Medicine.

The rate of U.S. adults older than 60 years reporting cognitive impairment increased among people of all races from 1997 to 2015 but less so among minority groups, according to data recently published in Preventing Chronic Disease.

Research published in PLOS One indicated that older adults who have positive beliefs about old age are less likely to develop dementia than those with negative age beliefs. Among carriers of the APOE 4 variant, positive age beliefs were linked to almost a 50% lower risk for dementia.

Older adults with metabolic syndrome have more severe symptoms and chronicity of depression and take longer to respond to antidepressant medications, according to research published in the Journal of the American Geriatrics Society.

Patients with dementia with Lewy bodies who took zonisamide as an adjunct to levodopa experienced improvements in parkinsonism without worsening cognitive function or psychiatric symptoms, according to study findings.

Study findings indicate that daily consumption of a curcumin supplement known as Theracurmin improved memory and mood in adults without dementia.