Alzheimer’s Disease/Dementia News

A neurotoxin derived from bacteria in the gastrointestinal tract has been identified as a major contributor to Alzheimer’s disease, researchers reported in Frontiers in Neurology.

Associations between cognitive ability in childhood and cognitive state in older age are moderated by how active and enriching one’s lifestyle remains through the middle years, according to a study published in Neurology.

Data from a genetics-based study show PCSK9 inhibition does not affect cognition function or dementia risk; however, statin use may be associated with some impaired cognitive performance that is outweighed by any CV benefits.

SAN DIEGO — Decline in dementia risk for Latino populations compared with white counterparts is associated with level of education across generations, a presenter said at the Alzheimer’s Association International Conference.

Atrial fibrillation conferred elevated risk for dementia in adults younger than 70 years, according to study findings published in the Journal of the American Heart Association.

The FDA has declined to approve a supplemental new drug application for the expanded use of Nuplazid to treat psychosis related to Alzheimer's disease.

SAN DIEGO — With prevalence of age-related cognitive decline and limited curative treatment options, nutritional interventions may prevent or delay symptom onset, per a presenter at the Alzheimer’s Association International Conference.

SAN DIEGO — A once-weekly dose of transdermal donepezil proved a safe and effective equivalent to a daily dose of oral donepezil for Alzheimer’s-related dementia, per a presenter at the Alzheimer’s Association International Conference.

SAN DIEGO — Substantial unmet end-of-life care needs among older adults with dementia exist in traditionally underrepresented groups compared with white individuals, according to a presenter at the Alzheimer’s Association International Conference.

SAN DIEGO — Cognitive reserve acted as a protective factor that preserved executive function in older adults with benefits mitigated by depression level, according to a presentation at the Alzheimer’s Association International Conference.