Alzheimer’s Disease/Dementia News

Neuropsychiatric and cognitive symptoms were common across the Alzheimer’s disease continuum but evolved differently during the course of the disease, according to results of a single-center observational study published in Neurology.

Results from a multicohort study of individuals in the U.S., U.K. and Europe revealed that people with high cognitively stimulating jobs were less likely to develop dementia in old age than those with low stimulating jobs.

Use of common clinical instruments helped identify progression of Lewy body dementia clinical features like global cognition and parkinsonism during a 6-month observation period, according to findings published in Neurology.

The FDA approval of Aduhelm, which was based on beta amyloid as a surrogate endpoint, represented a “regulatory failure,” according to members of an advisory committee convened by the FDA in November 2020.

Amyloid load appeared to negatively influence the progression of self-esteem among people at risk for Alzheimer’s dementia, according to study results published in Journal of Clinical Psychiatry.

Researchers are using natural language processing, mobile apps and telehealth to develop strategies that may someday assist primary care physicians with diagnosing cognitive decline and dementia.

Physical activity correlated with slower cognitive decline among people with both high and low tau concentrations, according to a population-based cohort study in JAMA Network Open.

Recent data revealed an increase in medication use among nursing home residents in Ontario, Canada, “with the potential for adverse effects” during the COVID-19 pandemic, according to researchers.

A modified Mediterranean-ketogenic diet appeared to lower the amount of cognitive decline in adults who were at risk for Alzheimer’s disease, a small pilot study showed.

Healio Psychiatry has compiled a list of its five most-viewed stories in July.