Pharmacology News

QT-prolonging medications are associated with an increased risk for sudden cardiac death, but research published in JAMA Internal Medicine showed that this risk was specifically linked to nonarrhythmic causes.

A new type of auto-brewery syndrome was recently identified in a woman with cirrhosis and poorly controlled diabetes, according to a case report published in the Annals of Internal Medicine.

Several physicians who spoke with Healio Primary Care applauded the FDA’s decision to make Pataday Twice Daily Relief and Pataday Once Daily Relief available over the counter to patients 2 years of age and older with itchy eyes associated with allergic conjunctivitis.

Calcium channel blockers that are often prescribed to older adults with hypertension can cause peripheral edema, which many physicians misinterpret as a new medical condition and subsequently prescribe diuretics, according to research published in JAMA Internal Medicine.

Acid-suppression medication may increase the odds for colonization by multidrug-resistant microorganisms, according to a meta-analysis published in JAMA Internal Medicine.

The FDA has recently approved Vyepti, the first IV calcitonin gene-related peptide blocker for migraine prevention in adults, according to a press release from the manufacturer.

This year, Biogen is expected to submit a Biologics License Application to the FDA for its anti-amyloid antibody, aducanumab. If approved, it will be the first new drug available to patients with Alzheimer’s disease in 16 years.

The use of macrolide antibiotics during pregnancy was associated with an increased risk for major malformations — particularly cardiovascular malformations — in children, according to research published in BMJ.

MAUI, HAWAII — Treating severe acne with isotretinoin comes with several important considerations, two experts told Maui Derm attendees.

Low-dose methotrexate — the most commonly used drug for systemic rheumatic diseases — was associated with small to moderate increased risks for skin cancer along with gastrointestinal, infectious, pulmonary and hematologic adverse events, according to a study published in the Annals of Internal Medicine.