Pharmacology News

Twice-daily budesonide oral suspension, or BOS, improved outcomes in pediatric patients with eosinophilic esophagitis, according to research presented at this year’s virtual American Academy of Allergy, Asthma and Immunology Annual Meeting.

Atorvastatin demonstrated no overall effect on the frequency or severity of muscle symptoms among individuals who previously reported severe muscle symptoms while on statins, compared with placebo, according to data published in The BMJ.

Abrocitinib combined with a medicated topical therapy was effective, well tolerated and improved quality of life in adolescents with atopic dermatitis, according to phase 3 results from the JADE TEEN Study.

Children born to mothers who used opioids and macrolide antibiotics do not have increased risks for major birth defects, according to two studies published in the BMJ.

Many adults aged at least 75 years are taking aspirin for primary CVD prevention despite lack of evidence, whereas many are not taking statins for primary CVD prevention despite strong evidence, researchers reported.

By substituting branded drugs requested by prescribers for generic versions, Medicare could have saved $997 million and patients could have saved $161 million in 2017, according to research published in JAMA Network Open.

Dupixent improved disease-specific, health-related quality of life and reduced symptoms in adolescents and adults with eosinophilic esophagitis, according to data from the American Academy of Allergy, Asthma and Immunology Annual Meeting.

The FDA announced that it has granted accelerated approval for Amondys 45 injections as a treatment for a rare form of Duchenne muscular dystrophy, according to a press release.

Prescription monitoring program data, “a vital tool to help combat the potential harms associated with prescription opioid misuse,” were underutilized by health care professionals, researchers wrote in Pain Medicine.

Maternal antibiotic use in the second and third trimester of pregnancy was associated with an increased risk for developing childhood asthma, according to research published in Archives of Diseases in Children.