Pharmacology News

Rates and severity of postpartum depression and anxiety symptoms among women who sought treatment for postpartum depression worsened during the COVID-19 pandemic.

State and local governments across the U.S. have reached an agreement with Johnson & Johnson, McKesson, Cardinal Health and AmerisourceBergen that will provide up to $26 billion to fight the opioid epidemic, the parties involved announced.

In a meta-analysis of omega-3 fatty acid trials, eicosapentaenoic acid monotherapy yielded the greatest reduction in CV risk vs. a combination of eicosapentaenoic acid and docosahexaenoic acid.

In a phase 3 trial of pimavanserin that came to a premature halt for efficacy, patients with dementia-related psychosis who continued the treatment had a lower risk for relapse than those who were switched to placebo, researchers reported.

The FDA requested removal of its contraindication against using cholesterol-lowering statin medicines among pregnant patients; however, most patients should stop statins once they learn they are pregnant.

Among older adults with atrial fibrillation, apixaban was linked to lower rates of adverse events across all frailty levels compared with warfarin, a retrospective observational study showed.

The effects of the SGLT2 inhibitor empagliflozin varied depending on region and racial/ethnic group, with the most benefit observed in those with the highest ratios of HF hospitalization to CV death, according to EMPEROR-Reduced trial data.

An intervention researchers hoped would improve infection management did not significantly reduce antimicrobial use among nursing home residents with dementia, data showed.

Pravastatin compared with placebo did not reduce incidence of delivery with preeclampsia among pregnant women at high risk, according to findings published in Circulation.

One-fifth of older patients discharged with gabapentin following a surgical procedure had the prescription refilled for more than 90 days, suggesting long-term use is common, according to an analysis of Medicare data.