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Pharmacology News
Statin therapy discrepancy reported for some patients with severe hypercholesterolemia
New data showed that 2% of patients receiving low- or moderate-intensity statin therapy had estimated severe hypercholesterolemia but received less aggressive therapy than those with maximum measured severe hypercholesterolemia.
HHS plan to lower prescription drug costs is a good start, but we need bold, swift action
HHS recently announced a plan supporting legislation that would allow it to negotiate Medicare Part B and Part D drug prices directly with pharmaceutical companies and then make those prices available to other purchasers.
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EMPEROR-Preserved: Empagliflozin reduces risk for serious hospitalizations in HFpEF
In patients with HF with preserved ejection fraction, empagliflozin reduced risk for serious hospitalizations compared with placebo, according to new data from the EMPEROR-Preserved trial.
Extended anticoagulant use for unprovoked VTE linked to ‘considerable’ bleeding risk
Patients who continued to use anticoagulant therapy beyond the initial 3 to 6 months of treatment for a first unprovoked venous thromboembolism were at “considerable” risk for major bleeding, researchers wrote.
HHS proposes legislation to lower prescription drug costs
HHS Secretary Xavier Becerra has announced a plan to lower prescription drug prices by “promoting negotiation, competition and innovation in the health care industry.”
Pharmacological BP reduction effective for lowering CV event risk regardless of age
Lowering BP through medication reduced risk for CV events across almost all age groups, suggesting age-related BP thresholds should be removed from guidelines, researchers reported at the European Society of Cardiology Congress.
Novel treatment effective against overactive bladder in phase 2 study
The novel muscarinic M3 receptor antagonist DA8010 significantly reduced urine frequency and urgency episodes compared with placebo in adults with overactive bladder, according to recent findings.
Web app for self-prescription of statins 96% concordant with physician reviewers
A web application to help individuals self-prescribe statin therapy demonstrated 96% agreement with subsequent physician judgment, according to research published in the Journal of the American College of Cardiology.
Dapagliflozin reduces risk for ventricular arrhythmia, cardiac arrest, sudden death
Compared with placebo, dapagliflozin reduced risk for ventricular arrhythmias, cardiac arrest and sudden death, according to new data from the DAPA-HF trial.
‘Alarmed’ AMA demands ‘immediate end’ to nonclinical trial use of ivermectin for COVID-19
Several medical organizations said they were vehemently “against the ordering, prescribing or dispensing of ivermectin to prevent or treat COVID-19” when it is not being used in a clinical trial.
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