Pharmacology News

Suboptimal uses of statin therapy, aspirin prescription and lifestyle counseling persist for adults with atherosclerotic CVD, despite new guidelines emphasizing their effect on reduced mortality, researchers reported.

Patients with injection drug use-associated infections were less likely to be readmitted to the hospital or die when they were treated by a clinical team that integrated infectious disease and substance use disorder care, researchers found.

Procedural-induced abortion may be slightly safer than pharmaceutical-induced abortion, although both are safe and effective, according to researchers.

In people with a family history of parental premature MI, aspirin for primary prevention was not associated with reduced CV events or overall mortality, according to data published in the European Journal of Preventive Cardiology.

For children and young adults with type 1 diabetes, comorbidities such as obesity and asthma increased the risk for COVID-19 hospitalization, according to study results published in Pediatric Diabetes.

New antimicrobial dispensing within 28 days of initial treatment was associated with uncomplicated UTIs where the uropathogen was not susceptible to initial treatment, according to a recent study.

Physician “nudges” via electronic health record prompts and peer comparison feedback improved statin prescription in the primary care setting for eligible patients compared with usual care, researchers reported.

The SGLT2 inhibitor dapagliflozin was associated with a reduced risk for hospitalization due to any cause in patients with chronic kidney disease with and without type 2 diabetes, according to a post hoc analysis of the DAPA-CKD trial.

New data published in The New England Journal of Medicine showed that buprenorphine use during pregnancy was associated with a lower risk for adverse neonatal outcomes compared with methadone use.

The ACP has released living, rapid practice points summarizing the best available evidence on the treatment of adults with confirmed mild or moderate COVID-19 in an outpatient setting.