Pharmacology News

FDA has eliminated the Risk Evaluation and Mitigation Strategy (REMS) programs for Lotronex (alosetron hydrochloride) and approved generics.

Nearly half of patients who responded to a survey said they stop antibiotic treatment early, usually because they feel better, and three-quarters said they keep the leftover antibiotics, often intending to use them in the future.

Doxycycline reduced the risk for Clostridioides difficile infection by almost half compared with azithromycin among patients hospitalized with community-acquire pneumonia who had a C. difficile infection in the past year, a study found.

BOSTON — A single dose of benzathine penicillin G is effective against early syphilis regardless of HIV status, according to a study presented at IDWeek.

BOSTON — In this Healio video exclusive, Paul M. Ridker, MD, MPH, discusses the use of low-dose colchicine to target inflammation in patients who remain at high CVD risk despite controlled LDL.

BOSTON — In this Healio video exclusive, Donna H. Ryan, MD, and Christopher Still, DO, FACP, discuss the optimal treatment strategy for patients who require weight loss beyond diet and lifestyle changes.

Highly effective new anti-obesity medications such as semaglutide and tirzepatide have led to a sea change in expectations for the treatment of obesity, giving new hope to individuals who have struggled with excess weight for years.

For patients with chronic pain, the right treatment could help prevent suicide, according to Kathleen M. Farrell, DO.

Constipation is a relatively common problem in pediatric practice, with reported prevalence rates between 1% and 30%, as well as the chief complaint in 3% to 5% of visits to pediatric outpatient clinics. Because most constipation cases can be remedied through recommended over-the-counter laxatives, constipation is rarely a cause for severe worry among parents.

Older individuals appeared to derive similar magnitude of LDL lowering and CV risk reduction from statin therapy initiation vs. younger patients, according to data from a large Danish study.