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Nephrology News
BMI impacts allograft outcomes in kidney transplant for recipients with type 2 diabetes
BOSTON — For transplant recipients with type 2 diabetes, delayed graft function was more common in those with higher BMIs and allograft survival was lowest in those categorized as obese or underweight, according to research presented at the American Transplant Congress.
Hypokalemia both before, after dialysis increases mortality risk
Having both pre- and post-dialysis hypokalemia increased the risk for mortality, according to data from Japan published in the Clinical Journal of the American Society of Nephrology.
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Cyclosporine maintenance therapy improves outcomes in lupus nephritis
Prolonged maintenance therapy with cyclosporine was associated with ongoing complete responses in a cohort of patients with lupus nephritis, according to recent findings presented at the EULAR Annual Congress.
Higher eGFR at dialysis initiation associated with increased mortality risk for pediatric patients
Children and adolescents who begin dialysis therapy with higher eGFRs may be at greater risk for mortality compared with those who have lower eGFRs at initiation, according to a published study.
HCV treatment with Epclusa safe in patients undergoing dialysis for ESRD
Although not currently licensed for patients undergoing dialysis for severe renal impairment, researchers found that treatment with Epclusa for hepatitis C was safe and effective in patients with end-stage renal disease.
Kidney transplant recipients, especially women, have increased risk of cardiovascular mortality
BOSTON — Kidney transplant recipients have a substantially greater risk of cardiovascular mortality than the general population, and excess risk is higher for women than men, according to a speaker at the American Transplant Congress.
Greater odds of allograft survival after dual kidney transplant than expanded criteria donor transplant
BOSTON — Although allograft survival was lower in dual kidney transplant when compared with standard criteria donor transplant, it was significantly higher in dual kidney transplant recipients than in expanded criteria donor recipients, according to research presented at the American Transplant Congress.
Donor-derived cell-free DNA test may accurately diagnose antibody- mediated rejection in pediatric kidney transplant recipients
BOSTON — A donor-derived cell-free DNA test that considers donor-specific antibodies may help predict antibody-mediated rejection in patients younger than 21 years of age, according to research presented at the American Transplant Congress.
Social support networks are essential for care of kidney transplant candidates but barriers exist to optimal engagement
BOSTON — After barriers to participating in the care of patients awaiting kidney transplant were reported by friends and family, researchers began investigating ways to empower these social support networks and to increase their engagement in the transplant process, according to Allyson Hart, MD, MS, of Hennepin County Medical Center in Minnesota.
Donor-derived cell-free DNA test may help detect graft rejection in kidney transplant recipients
BOSTON — A test that uses donor-derived cell-free DNA accurately discriminated rejection from non-rejection in kidney transplant recipients and was particularly effective in the discrimination of antibody-mediated rejection, according to research presented at the American Transplant Congress.