Hospital Medicine News

Oral tebipenem pivoxil hydrobromide is noninferior to IV ertapenem for the treatment of complicated UTI and acute pyelonephritis, according to the results of a phase 3 trial published in The New England Journal of Medicine.

Post-surgery opioid prescribing for children and teenagers declined between 2014 and 2019, with a sharp decline seen starting in late 2017, according to a study published in Pediatrics.

Ivermectin did not lower the incidence of hospitalization among high-risk adults with COVID-19 enrolled in a large double-blind, randomized, placebo-controlled trial in Brazil, researchers reported in The New England Journal of Medicine.

Cognitive impairment was more severe in hospitalized COVID-19 patients compared with those with other illnesses who required hospitalization, according to a study published in JAMA Psychiatry.

Older patients taking psychotropic medication were about three times more likely to develop dementia following a SARS-CoV-2 infection, researchers reported in Frontiers in Medicine.

WHO estimates there have been upwards of two attacks per day on health care infrastructure in Ukraine since Russia’s invasion of the country.

Strokes were reported to be a rare adverse event following the administration of a COVID-19 vaccine, according to a study in Neurology.

Among patients hospitalized with moderate COVID-19, those who received aspirin on the first day of hospitalization had a significantly lower risk for 28-day mortality than those who did not, according to a recent observational cohort study.

As of late February, just 64.5% of Americans were fully vaccinated against COVID-19, and less than half of eligible people had received a recommended booster dose.

Adding aerosolized hydrogen peroxide to hospital infection prevention protocols significantly reduced Clostridioides difficile infections, according to the results of a 10-year study reported in the American Journal of Infection Control.