Top in women's health: GLP-1 use before pregnancy; developments in male contraception
A retrospective study demonstrated that GLP-1 receptor agonist use before pregnancy corresponded with lower risks for hypertensive disorders of pregnancy, gestational diabetes, preterm birth and cesarean delivery.
“The next step would be to prospectively study patients prescribed GLP-1 receptor agonists to confirm the associations we saw in this study,” Christopher T. Nau, MD, assistant professor in the department of reproductive biology at Case Western Reserve University School of Medicine and the division of maternal fetal medicine at University Hospitals Cleveland Medical Center, told Healio.
It was the top story in women’s health last week.
In another top story, Healio spoke with an expert about reversible contraceptive methods for men and the implications of an approved male contraceptive transdermal gel.
Read these and more top stories in women’s health below:
Preconception GLP-1 receptor agonist use may reduce pregnancy risks
Women prescribed a GLP-1 receptor agonist up to 2 years before conception appeared less likely to develop hypertensive disorders of pregnancy, gestational diabetes, have a preterm birth or cesarean delivery, researchers reported. Read more.
‘Men have changed’: Growing interest in male contraception sparks transdermal gel research
Growing interest in male contraceptive options in the wake of the Dobbs decision and current abortion laws have spurred increased attention in development of a transdermal gel for men to block sperm production. Read more.
Unplanned cesarean delivery may increase postpartum depression risk
Women with an unplanned cesarean delivery had increased odds of developing postpartum depression and attending postpartum visits vs. those who delivered via planned cesarean or vaginally, researchers reported. Read more.
Second-trimester blood test predicts premature birth for average-risk women
Compared with usual care, a mid-trimester blood test designed to predict preterm birth for average-risk women markedly reduced neonatal morbidity when paired with a three-step treatment bundle, researchers reported at The Pregnancy Meeting. Read more.
Gravidity, beta-hCG level may predict methotrexate failure for ectopic pregnancy
For women with an ectopic pregnancy, higher gravidity, elevated beta-human chorionic gonadotropin levels and number of drug doses were predictors of methotrexate treatment failure, study results reported in BMC Pregnancy and Childbirth showed. Read more.