Top in cardiology: Erythritol raises thrombotic risk; bystander CPR survival disparities
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Consumption of the artificial sweetener erythritol may be linked with higher risk for blood clot formation compared with glucose in a study of 20 healthy volunteers published in Applied Microbiology and Biotechnology.
“Our earlier studies with erythritol showed in large-scale clinical observation studies that elevated blood erythritol levels were associated with incident risk of MI, stroke and death,” Stanley L. Hazen, MD, PhD, co-section head of preventive cardiology and chair of cardiovascular and metabolic sciences at the Cleveland Clinic Lerner Research Institute and Healio | Cardiology Today Editorial Board Member, told Healio. “Mechanistic studies — animal model, and blood based — all pointed to a prothrombotic effect with erythritol as the underlying mechanism.”
It was the top story in cardiology last week.
In another top story, white patients who received bystander CPR had significantly higher survival rates for out-of-hospital cardiac arrest compared with Black patients (P for interaction < .001). Men also had a higher chance for survival than women (P for interaction < .001).
Read these and more top stories in cardiology below:
Sugar substitute erythritol linked to elevated risk for blood clot formation
Erythritol, a nonnutritive sweetener generally recognized as safe by the FDA, demonstrated fast-acting prothrombotic properties not observed with traditional glucose in a small study. Read more.
Treatment effect of bystander CPR varies by race, sex
For patients with out-of-hospital cardiac arrest, bystander CPR improved rates of survival to hospital discharge, but the degree varied by race and sex, researchers reported in Circulation. Read more.
Top-line results: Finerenone reduces events in certain patients with heart failure
Bayer announced positive top-line results for the FINEARTS-HF trial of finerenone, in which the drug reduced risk for cardiovascular death and heart failure events in patients with HF with preserved or mildly reduced ejection fraction. Read more.
Q&A: New class of total artificial heart implanted successfully for first time
The first implantation of a new class of total artificial heart, a rotary pump with a single moving part, was successfully completed by a team at The Texas Heart Institute, the institution reported. Read more.
Q&A: Stanford Children’s heart transplant patients ‘not just surviving but thriving’
Stanford Medicine Children’s Health this year celebrated 50 years of pediatric heart transplants and more than 35 years of pediatric lung transplants. Read more.