Top in cardiology: Effects of vitamin D; new details on man’s death after xenotransplant
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A large trial of older adults found a reduction in cardiovascular events after vitamin D supplementation compared with placebo, a result that was inconsistent with previous studies, according to researchers.
Those who took vitamin D had lower rates of myocardial infarction (HR = 0.81; 95% CI, 0.67-0.98) and coronary revascularization (HR = 0.89; 95% CI, 0.78-1.01), although JoAnn E. Manson, MD, DrPH, MACP, FAHA, told Healio that the results are “likely chance findings.” It was the top story in cardiology last week.
Another top story covered research into the death of the man who received the world’s first genetically modified pig heart transplant. He died 2 months after the surgery in 2022.
Read these and more top stories in cardiology below:
Trial of vitamin D supplementation raises questions about CV effects on older adults
In a trial of more than 20,000 older adults, vitamin D supplementation trended toward reducing risk for major cardiovascular events in older adults compared with placebo, a finding differing from previous studies. Read more.
Overlapping causes likely contributed to man’s death after first pig heart xenotransplant
A combination of complex causes likely contributed to the death of the man who received the world’s first genetically modified pig heart transplant in 2022, including the presence of a latent porcine virus, researchers reported. Read more.
Eicosapentaenoic acid appears to counteract harmful CV effects from air pollution
Eicosapentaenoic acid, the active ingredient in certain omega-3 fatty acids, promoted anti-inflammatory, cytoprotective and lipid changes in endothelial cells exposed to air pollution, researchers reported. Read more.
Excessive drinking tied to coronary plaque burden in Chinese men
Self-reported and genotype-predicted mean alcohol intake are associated with a higher burden of carotid plaque among a cohort of Chinese men, but not carotid intima-media thickness, researchers reported. Read more.
Outcomes after HF hospitalization suboptimal, perhaps due to failure to follow guidelines
Among more than 250,000 patients hospitalized for heart failure for the first time in four countries, more than one-quarter died within 1 year of their hospitalization, according to the EVOLUTION HF cohort study. Read more.